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KMID : 0355420140380010010
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Journal of Korean Academy of Oral Health
2014 Volume.38 No. 1 p.10 ~ p.16
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Detection of early changes in caries lesion using QLF-D and OCT
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Ku Hye-Min
Kim Bo-Ra
Kang Si-Mook
Chung Jung-Ho
Kwon Ho-Keun
Kim Baek-Il
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Abstract
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Objectives: We aimed to compare the differences in caries lesion changes when measured by QLF-Das fluorescence loss and by SS-OCT as lesion depth with respect to demineralized time, duringformation of artificial early caries lesion. We also demonstrated that QLF-D and SS-OCT can be usedeffectively in monitoring the longitudinal progression of simulated caries lesions.
Methods: Ten bovine incisors were sectioned (5×4 mm) and embedded in epoxy resin. An acidresistantnail varnish was applied to a part of the tooth surfaces to protect sound enamel (2×4 mm). Togenerate lesions, each specimen was immersed in 40 ml of a demineralizing gel for 20 days at 37oC.To measure mineral loss of the demineralized specimens, fluorescence loss (ΔF, %) was measured byQLF-D and lesion depth (μm) was determined by SS-OCT from the captured cross-sectional image.All the specimens were analyzed daily by QLF-D image analysis software and SS-OCT image analysisprogram for 20 days. The repeated measures analysis of ΔF and lesion depth was used. The pairedt-test was used to assess differences between each day. The correlation between ΔF and lesion depthwas determined using the Pearson’s correlation coefficient.
Results: On the 5th, 10th, and 15th day, compared to baseline values, ΔF decreased in 12.7%, 25.0%,and 33.6% of the specimens, respectively, and the lesion depth increased in 9.9%, 16.0%, and 22.6%of the specimens, respectively. However, after 15 days, there was no change in the ΔF and lesiondepth. High significant correlation was identified between the resultant values of ΔF obtained by QLF-Dand those of lesion depth obtained by SS-OCT (r = ―0.811, P<0.0001).
Conclusions: The QLF-D and SS-OCT could detect subtle changes in mineral loss and lesion depthwith respect to demineralized time. Furthermore, these devices were useful for monitoring changes inmineral amount and lesion depth.
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KEYWORD
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Early dental caries, Longitudinal study, Optical coherence tomography, Quantitative light-induced fluorescence-digital
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